Tezacaftor
Brands containing Tezacaftor, food notes, and the most important drug interactions.
BRANDS
0No registered brands found for this active ingredient.
FOOD NOTES
3Avoid St. John's Wort. This herb induces CYP3A metabolism and may reduce serum levels of tezacaftor.
Template translationAvoid grapefruit products. Grapefruit inhibits CYP3A metabolism, which may increase the serum concentration of tezacaftor.
Template translationTake with food. Tezacaftor should be taken with fat-containing food to increase exposure.
Template translation
MOST IMPORTANT INTERACTIONS
first 10 of 50- AbataceptMODERATE
The metabolism of Tezacaftor can be increased when combined with Abatacept.
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- AcalabrutinibMODERATE
The metabolism of Tezacaftor can be decreased when combined with Acalabrutinib.
Expert view
- AcetylcysteineMODERATE
The excretion of Tezacaftor can be decreased when combined with Acetylcysteine.
Expert view
- AdalimumabMODERATE
The metabolism of Tezacaftor can be increased when combined with Adalimumab.
Expert view
- AfatinibMODERATE
The serum concentration of Tezacaftor can be increased when it is combined with Afatinib.
Expert view
- AfelimomabMODERATE
The metabolism of Tezacaftor can be increased when combined with Afelimomab.
Expert view
- AlfentanilMODERATE
The metabolism of Tezacaftor can be decreased when combined with Alfentanil.
Expert view
- AlprazolamMODERATE
The metabolism of Tezacaftor can be decreased when combined with Alprazolam.
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- AmbrisentanMODERATE
The serum concentration of Tezacaftor can be increased when it is combined with Ambrisentan.
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- AmiodaroneMODERATE
The metabolism of Tezacaftor can be decreased when combined with Amiodarone.
Expert view