Pazopanib
Brands containing Pazopanib, food notes, and the most important drug interactions.
BRANDS
4- VOPAZZI 200 MG FILM KAPLI TABLET (30 TABLET)barcode: 8699525099716
- VOPAZZI 400 MG FILM KAPLI TABLET (60 TABLET)barcode: 8699525099723
- VOTRIENT 200 MG 30 TABLETbarcode: 8699504092134
- VOTRIENT 400 MG 60 TABLETbarcode: 8699504092165
FOOD NOTES
4Avoid St. John's Wort. This herb induces CYP3A4 metabolism, which may reduce the serum concentration of pazopanib.
Template translationAvoid grapefruit products. Grapefruit inhibits CYP3A4 metabolism, which may increase the serum concentration of pazopanib.
Template translationTake on an empty stomach. Separate pazopanib from meals by at least 1 hour before and 2 hours after eating as food increases pazopanib bioavailability.
Template translationTake separate from antacids. Separate the administration of pazopanib and antacids by several hours.
Template translation
MOST IMPORTANT INTERACTIONS
first 10 of 50- BenzocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Pazopanib is combined with Benzocaine.
Expert view
- BupivacaineMAJOR
The risk or severity of methemoglobinemia can be increased when Pazopanib is combined with Bupivacaine.
Expert view
- ChloroprocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Pazopanib is combined with Chloroprocaine.
Expert view
- CinchocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Pazopanib is combined with Cinchocaine.
Expert view
- CocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Pazopanib is combined with Cocaine.
Expert view
- DiphenhydramineMAJOR
The risk or severity of methemoglobinemia can be increased when Pazopanib is combined with Diphenhydramine.
Expert view
- DyclonineMAJOR
The risk or severity of methemoglobinemia can be increased when Pazopanib is combined with Dyclonine.
Expert view
- EsomeprazoleMAJOR
Esomeprazole can cause a decrease in the absorption of Pazopanib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Expert view
- LevobupivacaineMAJOR
The risk or severity of methemoglobinemia can be increased when Pazopanib is combined with Levobupivacaine.
Expert view
- LidocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Pazopanib is combined with Lidocaine.
Expert view