Lumateperone
Brands containing Lumateperone, food notes, and the most important drug interactions.
BRANDS
0No registered brands found for this active ingredient.
FOOD NOTES
3Avoid St. John's Wort. This herb induces the CYP3A4 metabolism of lumateperone, causing a reduction in its serum concentration.
Template translationAvoid grapefruit products. Grapefruit inhibits the CYP3A4 metabolism of lumateperone, which may increase its serum concentration.
Template translationTake with food. Administration with food reduces the Cmax by 33% and prolongs the Tmax by one hour.
Template translation
MOST IMPORTANT INTERACTIONS
first 10 of 50- OliceridineMAJOR
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Lumateperone is combined with Oliceridine.
Expert view
- Tedizolid phosphateMAJOR
The risk or severity of serotonin syndrome can be increased when Tedizolid phosphate is combined with Lumateperone.
Expert view
- 2,5-Dimethoxy-4-ethylamphetamineMODERATE
Lumateperone may decrease the stimulatory activities of 2,5-Dimethoxy-4-ethylamphetamine.
Expert view
- 4-Bromo-2,5-dimethoxyamphetamineMODERATE
Lumateperone may decrease the stimulatory activities of 4-Bromo-2,5-dimethoxyamphetamine.
Expert view
- 4-MethoxyamphetamineMODERATE
The risk or severity of CNS depression can be increased when 4-Methoxyamphetamine is combined with Lumateperone.
Expert view
- 7-NitroindazoleMODERATE
The risk or severity of CNS depression can be increased when 7-Nitroindazole is combined with Lumateperone.
Expert view
- AcepromazineMODERATE
The risk or severity of adverse effects can be increased when Lumateperone is combined with Acepromazine.
Expert view
- AceprometazineMODERATE
The risk or severity of adverse effects can be increased when Lumateperone is combined with Aceprometazine.
Expert view
- AcetaminophenMODERATE
The serum concentration of Lumateperone can be decreased when it is combined with Acetaminophen.
Expert view
- AcetazolamideMODERATE
The risk or severity of CNS depression can be increased when Acetazolamide is combined with Lumateperone.
Expert view