Clozapine
Brands containing Clozapine, food notes, and the most important drug interactions.
BRANDS
2- CLONEX 100 MG 50 TABLETbarcode: 8699587012449
- CLONEX 25 MG 50 TABLETbarcode: 8699587012432
FOOD NOTES
4Avoid alcohol. Alcohol is a predisposing risk factor for seizure in combination with clozapine.
Template translationExercise caution with St. John's Wort. This herb induces both CYP3A4 and CYP1A2 metabolism and may reduce clozapine serum levels.
Template translationLimit caffeine intake. Caffeine may reduce clozapine metabolism.
Template translationTake with or without food. The absorption is unaffected by food.
Template translation
MOST IMPORTANT INTERACTIONS
first 10 of 50- CarbamazepineMAJOR
The serum concentration of Clozapine can be decreased when it is combined with Carbamazepine.
Expert view
- CiprofloxacinMAJOR
The serum concentration of Clozapine can be increased when it is combined with Ciprofloxacin.
Expert view
- CyclobenzaprineMAJOR
The risk or severity of CNS depression can be increased when Cyclobenzaprine is combined with Clozapine.
Expert view
- DiphenhydramineMAJOR
The serum concentration of Clozapine can be increased when it is combined with Diphenhydramine.
Expert view
- EnoxacinMAJOR
The risk or severity of QTc prolongation can be increased when Enoxacin is combined with Clozapine.
Expert view
- EtrasimodMAJOR
The risk or severity of QTc prolongation and torsade de pointes can be increased when Etrasimod is combined with Clozapine.
Expert view
- OliceridineMAJOR
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Clozapine is combined with Oliceridine.
Expert view
- RifampinMAJOR
The serum concentration of Clozapine can be decreased when it is combined with Rifampicin.
Expert view
- FluvoxamineMAJOR
The serum concentration of Clozapine can be increased when it is combined with Fluvoxamine.
Expert view
- PhenytoinMAJOR
The serum concentration of Clozapine can be decreased when it is combined with Phenytoin.
Expert view