Rifabutin

含有 Rifabutin 的品牌、食物注意事项以及最重要的药物相互作用。

品牌

MYCOBUTIN 150 MG 30 KAPSUL条形码：8681308151094

食物注意事项

可随餐或空腹服用。
模板翻译

最重要的相互作用

前 10 项，共 50 项

Cabotegravir禁忌
Rilpivirine 25 mg 每日一次 300 mg 每日一次健康受试者（18）ND ↓ AUC 42% ↓ C min 48% ↓ C max 31% 不建议 rifabutin 与 Odefsey（rilpivirine/tenofovir alafenamide/emtricitabine）合用，因为除已报告的 rilpivirine 降低外，预计 tenofovir alafenamide 也会降低。
专业视图
Rilpivirine 25 mg once a day 300 mg once a day Healthy subjects (18) ND ↓ AUC by 42% ↓ C min by 48% ↓ C max by 31% Co-administration of rifabutin with Odefsey (rilpivirine/tenofovir alafenamide/emtricitabine) is not recommended, due to an expected decrease in tenofovir alafenamide in addition to the reported reduction in rilpivirine.
来源：FDA openFDA
Rilpivirine禁忌
当 Rilpivirine 与 Rifabutin 联合使用时，Rilpivirine 的血药浓度可能降低。
专业视图
The serum concentration of Rilpivirine can be decreased when it is combined with Rifabutin.
Voriconazole禁忌
当 Voriconazole 与 Rifabutin 联合使用时，Voriconazole 的血药浓度可能降低。
专业视图
The serum concentration of Voriconazole can be decreased when it is combined with Rifabutin.
Bupivacaine重大
当 Rifabutin 与 Bupivacaine 联合使用时，发生高铁血红蛋白血症的风险或严重程度可能增加。
专业视图
The risk or severity of methemoglobinemia can be increased when Rifabutin is combined with Bupivacaine.
Cinchocaine重大
当 Rifabutin 与 Cinchocaine 联合使用时，发生高铁血红蛋白血症的风险或严重程度可能增加。
专业视图
The risk or severity of methemoglobinemia can be increased when Rifabutin is combined with Cinchocaine.
Dapsone重大
当 Dapsone 与 Rifabutin 联合使用时，Dapsone 的代谢可能加快。
专业视图
The metabolism of Dapsone can be increased when combined with Rifabutin.
Lidocaine重大
当 Rifabutin 与 Lidocaine 联合使用时，发生高铁血红蛋白血症的风险或严重程度可能增加。
专业视图
The risk or severity of methemoglobinemia can be increased when Rifabutin is combined with Lidocaine.
Phenindione重大
当 Rifabutin 与 Phenindione 联合使用时，发生出血的风险或严重程度可能增加。
专业视图
The risk or severity of bleeding can be increased when Rifabutin is combined with Phenindione.
Ranolazine重大
当 Ranolazine 与 Rifabutin 联合使用时，Ranolazine 的代谢可能加快。
专业视图
The metabolism of Ranolazine can be increased when combined with Rifabutin.
4-hydroxycoumarin重大
当 Rifabutin 与 4-hydroxycoumarin 联合使用时，发生出血的风险或严重程度可能增加。
专业视图
The risk or severity of bleeding can be increased when Rifabutin is combined with 4-hydroxycoumarin.