Rucaparib
Brands containing Rucaparib, food notes, and the most important drug interactions.
BRANDS
0No registered brands found for this active ingredient.
FOOD NOTES
3Exercise caution with St. John's Wort. Rucaparib is primarily metabolized through CYP2D6 but is also metabolized by CYP3A4 and CYP1A2. St. John's Wort induces CYP3A4 metabolism, which may reduce rucaparib serum levels.
Template translationExercise caution with grapefruit products. Rucaparib is primarily metabolized through CYP2D6 but is also metabolized by CYP3A4 and CYP1A2. Grapefruit inhibits CYP3A4 metabolism, which may increase rucaparib serum levels.
Template translationTake with or without food. A high-fat meals increases drug exposure but not to a clinically significant extent.
Template translation
MOST IMPORTANT INTERACTIONS
first 10 of 50- AmbroxolMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Ambroxol.
Expert view
- ArticaineMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Articaine.
Expert view
- ButacaineMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Butacaine.
Expert view
- ButambenMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Butamben.
Expert view
- CapsaicinMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Capsaicin.
Expert view
- ChloroprocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Chloroprocaine.
Expert view
- CinchocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Cinchocaine.
Expert view
- CocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Cocaine.
Expert view
- DyclonineMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Dyclonine.
Expert view
- EtidocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Rucaparib is combined with Etidocaine.
Expert view