Regorafenib

Brands containing Regorafenib, food notes, and the most important drug interactions.

BRANDS

Avoid St. John's Wort. This herb induces CYP3A4 metabolism, which may reduce serum levels of regorafenib.
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Avoid grapefruit products. Grapefruit inhibits CYP3A4 metabolism, which may increase the serum levels of regorafenib.
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Take after a meal. Should be taken following a low-fat meal containing less than 600 calories and less than 30% fat.
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Take at the same time every day.
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AmbroxolMAJOR
The risk or severity of methemoglobinemia can be increased when Regorafenib is combined with Ambroxol.
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BenzocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Regorafenib is combined with Benzocaine.
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Benzyl alcoholMAJOR
The risk or severity of methemoglobinemia can be increased when Regorafenib is combined with Benzyl alcohol.
Expert view
BupivacaineMAJOR
The risk or severity of methemoglobinemia can be increased when Regorafenib is combined with Bupivacaine.
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CapsaicinMAJOR
The risk or severity of methemoglobinemia can be increased when Regorafenib is combined with Capsaicin.
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CarbamazepineMAJOR
The metabolism of Regorafenib can be increased when combined with Carbamazepine.
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ChloroprocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Regorafenib is combined with Chloroprocaine.
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CinchocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Regorafenib is combined with Cinchocaine.
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ClarithromycinMAJOR
The metabolism of Regorafenib can be decreased when combined with Clarithromycin.
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CocaineMAJOR
The risk or severity of methemoglobinemia can be increased when Regorafenib is combined with Cocaine.
Expert view