Nirogacestat
Brands containing Nirogacestat, food notes, and the most important drug interactions.
BRANDS
0No registered brands found for this active ingredient.
FOOD NOTES
3Avoid grapefruit products. Nirogacestat is a CYP3A substrate and grapefruit is a known CYP3A inhibitors.
Template translationTake separate from antacids. take nirogacestat 2 hours before or 2 hours after taking the antacid.
Template translationTake with or without food.
Template translation
MOST IMPORTANT INTERACTIONS
first 10 of 50- (R)-warfarinMODERATE
The metabolism of (R)-warfarin can be increased when combined with Nirogacestat.
Expert view
The metabolism of Nirogacestat can be decreased when combined with 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine.
Expert view
- 4-MethoxyamphetamineMODERATE
The metabolism of Nirogacestat can be decreased when combined with 4-Methoxyamphetamine.
Expert view
- AbametapirMODERATE
The serum concentration of Nirogacestat can be increased when it is combined with Abametapir.
Expert view
- AbataceptMODERATE
The metabolism of Nirogacestat can be increased when combined with Abatacept.
Expert view
- AbemaciclibMODERATE
The serum concentration of Abemaciclib can be increased when it is combined with Nirogacestat.
Expert view
- AbirateroneMODERATE
The metabolism of Nirogacestat can be decreased when combined with Abiraterone.
Expert view
- AcebutololMODERATE
The metabolism of Nirogacestat can be decreased when combined with Acebutolol.
Expert view
- AcenocoumarolMODERATE
The metabolism of Acenocoumarol can be increased when combined with Nirogacestat.
Expert view
- AcetaminophenMODERATE
The metabolism of Nirogacestat can be decreased when combined with Acetaminophen.
Expert view