Nifedipine

Brands containing Nifedipine, food notes, and the most important drug interactions.

BRANDS

Avoid excessive or chronic alcohol consumption.
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Avoid grapefruit products. Grapefruit down-regulates post-translational expression of CYP3A4, the major metabolizing enzyme of nifedipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of nifedipine and may cause toxicity. Avoid grapefruit products while on this medication.
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Avoid natural licorice.
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Take with or without food.
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DarunavirMAJOR
The serum concentration of Nifedipine can be increased when it is combined with Darunavir.
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EtrasimodMAJOR
The risk or severity of QTc prolongation and torsade de pointes can be increased when Etrasimod is combined with Nifedipine.
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AbacavirMODERATE
Abacavir may decrease the excretion rate of Nifedipine which could result in a higher serum level.
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AcarboseMODERATE
Nifedipine may decrease the hypoglycemic activities of Acarbose.
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AcetaminophenMODERATE
Nifedipine may increase the hepatotoxic activities of Acetaminophen.
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AcetazolamideMODERATE
Acetazolamide may increase the excretion rate of Nifedipine which could result in a lower serum level and potentially a reduction in efficacy.
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AcetohexamideMODERATE
The risk or severity of hypoglycemia can be increased when Nifedipine is combined with Acetohexamide.
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AcetyldigitoxinMODERATE
Acetyldigitoxin may increase the arrhythmogenic activities of Nifedipine.
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Acetylsalicylic acidMODERATE
The risk or severity of hyperkalemia can be increased when Acetylsalicylic acid is combined with Nifedipine.
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AcyclovirMODERATE
The metabolism of Nifedipine can be decreased when combined with Acyclovir.
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