Levoketoconazole
Brands containing Levoketoconazole, food notes, and the most important drug interactions.
BRANDS
0No registered brands found for this active ingredient.
FOOD NOTES
2Avoid excessive or chronic alcohol consumption. Concomitant alcohol consumption may result in a disulfiram-like reaction characterized by rash, flushing, peripheral edema, nausea, and headache. These symptoms typically subside within hours.
Template translationTake with or without food. In healthy subjects administered a single 600 mg oral dose of levoketoconazole, a high-fat meal increased the AUC by 30% with no change in the maximum plasma concentration but a delay to reach this value of between two and four hours. These changes are not considered clinically significant.
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MOST IMPORTANT INTERACTIONS
first 10 of 50- EtrasimodMAJOR
The risk or severity of QTc prolongation and torsade de pointes can be increased when Etrasimod is combined with Levoketoconazole.
Expert view
- SimvastatinMAJOR
The risk or severity of myopathy and rhabdomyolysis can be increased when Levoketoconazole is combined with Simvastatin.
Expert view
- 5-androstenedioneMODERATE
The metabolism of 5-androstenedione can be decreased when combined with Levoketoconazole.
Expert view
- AcenocoumarolMODERATE
The metabolism of Acenocoumarol can be decreased when combined with Levoketoconazole.
Expert view
- AcetaminophenMODERATE
The metabolism of Acetaminophen can be decreased when combined with Levoketoconazole.
Expert view
- AcyclovirMODERATE
The excretion of Acyclovir can be decreased when combined with Levoketoconazole.
Expert view
- AdinazolamMODERATE
The metabolism of Adinazolam can be decreased when combined with Levoketoconazole.
Expert view
- AlbendazoleMODERATE
The metabolism of Albendazole can be decreased when combined with Levoketoconazole.
Expert view
- AldosteroneMODERATE
The metabolism of Aldosterone can be decreased when combined with Levoketoconazole.
Expert view
- AlfentanilMODERATE
The metabolism of Alfentanil can be decreased when combined with Levoketoconazole.
Expert view